7 Keto DHEA vs DHEA for Adrenal Fatigue: Complete Guide

7 keto dhea vs dhea for adrenal fatigue
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7 Keto DHEA vs DHEA for Adrenal Fatigue

Both 7-Keto DHEA and DHEA have been marketed as weight loss supplements and as sources of a variety of other benefits, such as lowering the impact of inflammatory disorders like rheumatoid arthritis and minimizing memory loss. Keto DHEA cannot synthesize sex hormones, whereas DHEA encourages their production. Due to the fact that Keto DHEA avoids several of the issues connected with DHEA, researchers believe it may be safer.

What Is DHEA?

DHEA is a hormone called dehydroepiandrosterone produced by the adrenal glands. The stress hormone is released into your body by the adrenal glands, which are slightly above your kidneys. DHEA is a precursor to the hormone androstenedione, which the body uses to make the sex hormones, androgen (male sex hormones) and estrogen (female sex hormones) for both sexes.

DHEA levels in your body drop as you get older and some medications may also deplete them. It is a nutritional supplement that comes in tablet and capsule form. DHEA’s use as a weight-loss supplement is one of its key selling points.

DHEA is a hormone that supports cortisol. It serves as your “stress reserve tank”. Stress depletes DHEA, and as we become older, our DHEA production declines. DHEA can be replaced by taking over-the-counter supplements. Men can consume regular DHEA.

However, women should take a metabolite of DHEA called 7 Keto DHEA. 7 keto DHEA is sometimes preferred because instead of changing into other hormones like estrogen and testosterone, it remains in the body as DHEA. They are used for adrenal fatigue.

  • Dosage for Men: 50-100 mg per day.
  • Dosage for Women: 100-200 mg per day.

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What Is Adrenal Fatigue?

When the adrenal glands are unable to produce enough cortisol for our bodies to operate during the day, it results in adrenal fatigue (hypoadrenia). Hypothalamic-pituitary-adrenal (HPA) axis dysfunction, commonly known as adrenal fatigue, is an indication that the brain is not delivering or receiving signals from the adrenal glands.

What Is Cortisol?

The adrenal glands, located above each kidney, create the steroid hormone cortisol. Cortisol can act on different body parts after being released into the bloodstream and can help:

  • When the body is under stress or danger.
  • Accelerate the body’s glucose metabolism.
  • Regulate blood pressure.
  • Decrease inflammation.
  • Cortisol is required for the fight-or-flight response, a healthy, natural reaction to perceived threats. Your body controls the production of cortisol to maintain the proper balance.

What Causes the Production of Cortisol By the Adrenal Glands?

The pituitary gland controls the adrenal glands’ ability to produce cortisol. Because of its broader impacts on the body, the pituitary, a pea-sized gland at the base of the brain, is occasionally referred to as the “master gland.”

A hormone called cortisol is primarily released during stressful situations. There are numerous crucial roles for cortisol in the body. Having the right amount of balance is essential for human health, and complications might arise if you make too much or too little cortisol. This can lead to adrenaline fatigue.

Your pituitary gland responds when you wake up, exercise, or are dealing with a stressful situation. It instructs the adrenal glands to create the ideal amount of cortisol.

Not only does the body require cortisol during times of stress, but it is also one of the main hormones that regulate the body. All of our cells’ metabolic rates are regulated by cortisol.

Prolonged stress is the most frequent cause of signal disruption between the brain and the adrenal glands. Other contributing factors include having too many toxins in the body, an unhealthy lifestyle such as lack of sleep, eating insufficient fruits and vegetables, and consuming too much sugar, alcohol, and caffeine.

What Happens if your Cortisol Levels are Too High or Too Low?

The proper quantity of cortisol is usually produced by the body. It produces too much when someone has a disorder like Cushing’s syndrome. Meanwhile, it doesn’t produce enough when someone has a disorder like Addison’s disease. 

If cortisol levels are also discovered to be low, they can be raised by utilizing either the precursor pregnenolone or low dosage cortisol. 

Symptoms of Too Much Cortisol

Too much cortisol can cause:

  • Weight gain, particularly around the abdomen and face. 
  • Thin and fragile skin that heals slowly. 
  • Acne.
  • For women, facial hair and irregular menstrual periods.

Symptoms of not enough cortisol include: 

  • Continual tiredness. 
  • Nausea and vomiting. 
  • Weight loss. 
  • Muscle weakness. 
  • Pain in the abdomen. 

Your doctor might advise getting a blood test to check your cortisol levels if you have any of these symptoms.

What Is 7 Keto DHEA?

7 Keto, also known as 3-acetyl-7oxo-dehydroepiandrosterone is a naturally occurring metabolite that is largely produced by the adrenal glands, skin, and, to a lesser extent the brain. Similar to DHEA, 7-Keto reaches its peak in our early 20s and gradually drops to roughly 50% by age 50.

7-Keto DHEA (commonly referred to as 7 Keto) is one of the most significant DHEA metabolites. 7 Keto does not convert to estrogen or testosterone as DHEA does. This makes it preferable and contributes to its uses among its other benefits.

It has also been utilized in clinical practice to support thermogenesis-based fat reduction. These pathways aid in maintaining normal triglyceride levels as well.

7 Keto should be taken twice a day, in the morning and mid-afternoon, at a dose of 25 mg each time. It can be taken to greater levels as needed. This supports the body’s natural biorhythm and enables the support of balanced cortisol levels, which are high in the morning and decrease throughout the day.

It is also worth noting that 7 Keto can help treat Raynaud’s Syndrome, a condition in which some parts of your body, such as your fingers and toes, become numb and chilly in reaction to cold temperatures or stress. Obesity, immune and mental health, muscle strength, anxiety, depression, aging, and other problems are all treated with 7-Keto DHEA.

DHEA vs 7-Keto DHEA

Keto DHEA, which is also known as 7 Keto, is a DHEA metabolite. However, because Keto DHEA does not break down into the sex hormones estrogen or testosterone, it avoids many of the adverse effects associated with the parent product.

When taken for weight loss, keto DHEA has been found to be efficacious. Keto DHEA has been shown in studies to enhance the levels of the thyroid hormone T3, which aids in the regulation of your body’s metabolism.

In one trial, 30 persons were divided into two groups: those who received a placebo and those who received 200 mg of Keto DHEA daily. Patients who got Keto DHEA lost an average of 6.34 pounds throughout the eight-week research, whereas those that received the placebo dropped only 2.2 pounds.

Although 7 Keto DHEA and DHEA are similar, their effects can differ. 7 Keto may have higher psychological impacts than DHEA while having no effect on sex hormones.

DHEA has a variety of impacts when converted to sex hormones – androgens. Unlike DHEA, the 7 keto form cannot be converted into testosterone or estrogens in the steroid metabolic pathway, eliminating the possibility of boosting testosterone or estrogens.

DHEA and 7 Keto have advantages over each other. DHEA is preferred over 7 Keto DHEA for several reasons:

DHEA Can Be Measured

DHEA may be measured via blood or saliva tests, allowing doses to be tailored to the person, however, 7 Keto cannot be measured and thus doses are guessed.

DHEA Is Less Expensive

Years of patient feedback indicate that DHEA is more beneficial than its 7 Keto metabolite in addressing adrenal fatigue symptoms. With a lesser dosage, it has a larger effect on improving your metabolism. This means that you need to spend less to address the fatigue problem.

More Research Has Been Conducted on DHEA

There have been more studies on DHEA than on 7 Keto DHEA. DHEA conversion into sex hormones is one of them.

DHEA Health Advantages

DHEA has been found in studies to be effective in increasing adrenal hormone levels, making it a prospective treatment for those suffering from adrenal insufficiency, a critical medical condition in which the adrenal glands fail to synthesize enough of the important hormones – cortisol and aldosterone. Depression and obesity are two other health conditions that may benefit from DHEA supplements, however further research is needed on this.

DHEA has been used to promote fertility and increase sex drive because it is related to sex hormones. It can also help reduce the inflammation caused by rheumatoid arthritis and lupus.

It is highly advised that before taking DHEA or any supplements, you should always check your doctor for safety reasons.

The Benefits of Using DHEA

(1) Fatigue – Overcoming fatigue and adrenal depletion is one of the most common reasons DHEA is recommended.

When the adrenal glands’ production of DHEA and/or cortisol is consistently low for most of the day, you will experience the following symptoms: low energy, feeling tired all the time, depression, headaches, dark circles under the eyes, lack of mental alertness, salt and/or sugar cravings, edema, lightheadedness, heartburn, inability to tolerate the exercise, low blood pressure, being mentally and emotionally overstressed, chronic infections, and sleeping problems.

Continuous deficiency in DHEA will eventually result in hormonal cascade effects that will negatively affect thyroid and sex hormone levels, culminating in extremely bad health. DHEA supplementation relieves the chronic stress on your adrenal glands, restoring energy levels and stamina within a few weeks.

(2) Immune Function – Animal studies and clinical trial suggests that DHEA protects against viral, bacterial, and parasitic infections. It has been proposed that the increasing cortisol/DHEA ratio associated with aging suppresses cellular immunity.

DHEA has been shown to greatly enhance immunological mediators such as monocytes, B cells, T-cell receptors, and natural killer cells in aging men and women. DHEA supplementation for immune-compromised disorders such as chronic fatigue syndrome and AIDS strengthens the immune response, boosting energy levels, alleviating depression, and sharpening thinking.

(3) Osteoporosis – DHEA has been shown to boost bone growth and calcium uptake while inhibiting bone resorption.

(4) Aging – Preliminary findings indicate that DHEA can slow the aging process. After several weeks of therapy, it is able to improve muscular atrophy, weakness, tremulousness, and other indications of aging.

(5) Heart Disease – DHEA has been found to lower cholesterol levels, inhibit blood clot formation, and stimulate blood vessel relaxation, all of which help prevent heart disease.

(6) Improves Libido – DHEA can revitalize sex drive in older men and women.

(7) DHEA has been found to help with autoimmune disorders like systemic lupus erythematosus, rheumatoid arthritis, and inflammatory bowel disease. It is now being studied for the treatment of a variety of cancers, including breast cancer, colon cancer, and liver cancer. It has also been demonstrated to increase memory, improve mood, and provide a sense of well-being.

DHEA Complications

DHEA is considered potentially safe by the National Institutes of Health when used in tiny dosages and for no more than a few months. Dosages more than 50 mg to 100 mg per day used for more than a few months increase the probability of adverse effects.

They might range from simple symptoms like acne and stomach irritation to more serious ones like high blood pressure and liver failure. DHEA should be avoided by women with hormone disorders, such as fibroids and breast cancer, and it is not recommended for children under the age of 18 since it may interfere with their growth.

Adrenal Fatigue and DHEA

Dehydroepiandrosterone (DHEA) is a hormone produced by your body’s adrenal gland. DHEA aids in the production of other hormones such as testosterone and estrogen.

Natural DHEA levels peak in early adulthood and then gradually decline as you become older. DHEA is available in the form of a tablet, capsule, powder, topical cream, and gel.

DHEA is used as an anti-aging therapy to enhance physical performance. DHEA is also used to treat depression and menopausal symptoms.

Proper Understanding of Adrenal Fatigue

The human body was not designed for long-term stress, but rather for urgent danger. Cortisol alters our bodies in order to safeguard our lives in the face of danger. Cortisol is released in times of danger or stress to prevent shock, which could lead to major health problems.

Cortisol raises blood sugar levels in our body to ensure that our muscles and brain have the fuel they need to absorb shock and avoid danger.

Cortisol stimulates a component of our immune system to create inflammation in the event that a dangerous animal attack and bites us; our blood clots well, allowing us to continue running. It also inhibits another portion of our immune system, which aids in the fight against infections and cancer; the body isn’t concerned about cancer when confronted with a hazardous animal like a lion!

Furthermore, because the body isn’t preoccupied with digesting and absorbing meals at that time, blood flow to our intestines reduces.

While these physical modifications are necessary for survival, they only occur for brief, intermittent periods of time. Cortisol levels that are excessively high or too low for an extended period of time produce negative changes in the body.

Blood sugar that is consistently elevated leads to weight gain and diabetes. If the cortisol levels are excessively high or too low, it stresses the adrenal gland to work, thereby leading to adrenal fatigue. This causes chronic inflammation in the body.

Chronic inflammation causes a variety of medical issues, including hypertension, asthma, allergies, arthritis, obesity, and muscle and joint discomfort.

We are more susceptible to viral infections, autoimmunity, and cancer when our natural killer cells are consistently inhibited. Constipation, diarrhea, or irritable bowel syndrome are all symptoms of reduced blood flow to the intestines.

Who Can Benefit from 7 Keto DHEA?

If you have observed a change in your metabolism, you might think about incorporating 7Keto into your current wellness program.

7 Keto DHEA has been demonstrated to increase metabolic rate when combined with a healthy diet and exercise.

7 Keto DHEA may provide positive results on performance-enhancing drug tests and should be avoided if you are subject to such testing. When used topically, 7 Keto may have an effect on hormones in the body.

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How Should You Take 7 Keto?

If you’re interested in 7 Keto DHEA for its ability to help you maintain a healthy weight, keep in mind that it works best as one tool in a wider toolbox. Supplementation is typically combined with exercise and nutrition programs in effective human research on 7 Keto.

7 Keto DHEA is often available in the form of oral capsules and topical gels. It should be noted that gels pose a significant risk of altering hormone function, and you should consult your doctor before purchasing or using one.

Look for an oral supplement and take 200 milligrams each day, which is the clinically proven effective dose. Some people report nausea after using 7 Keto pills. Taking them with plenty of water and food can be helpful.

7 Keto DHEA Side Effects

Because of the scarcity of well-designed clinical investigations, the safety profile of 7 Keto DHEA is uncertain. The list of potential adverse effects below is not exhaustive; you should see your doctor about other potential side effects based on your health status and potential drug or supplement interactions.

In preliminary clinical trials, 7 Keto was found to be safe and well tolerated. It had mild negative effects in some patients, including;

7-Keto DHEA Dosing

The optimum dose of 7 Keto DHEA for treatment is determined by various factors, including the user’s age, health, and other circumstances. There is currently insufficient scientific evidence to define an optimal range of doses for 7 Keto DHEA. Remember to read the product label and speak with your pharmacist, doctor, or other healthcare professionals before using.

Cortisol Reduction and Cardiovascular Health

Cortisol levels will rise after a brief period of stress but will drop swiftly if the stress is extended. In one study, 10 healthy males were given 7 Keto (25 mg single doses) gel to apply to their skin. Cortisol levels dropped by 7.4% after five days.

7 Keto also boosted HDL cholesterol and apolipoprotein A-I in the same study, lowering the risk of clogged arteries and cardiovascular disease, particularly in older people. It had no hormonal adverse effects, making it a possible safe substitute for DHEA

Importance of Using 7 Keto DHEA

Memory Improvement

In one study, researchers discovered that 7 Keto DHEA supplements have the potential to improve cognitive function in both young and old mice with memory impairment. In young mice, the effect was significantly stronger, with 7 Keto totally reversing memory loss.

Thyroid Function and Depression

Chronic mild stress lowered thyroid hormones and immunological response (T cells) in mice with induced depression, according to one study. Scientists discovered that 7 Keto DHEA has the potential to alleviate depressive symptoms while also restoring thyroid hormone and immune cell levels to normal.

7 Keto DHEA vs DHEA for Adrenal Fatigue – Conclusion

In conclusion, 7 Keto and DHEA are two important supplements that can help individuals with adrenaline fatigue. They can be used to help individuals who have a high level of stress and anxiety as well as other health issues such as obesity, and aging, and for other benefits listed above.

Weight loss benefits of 7 Keto supplement: According to preliminary studies, 7 Keto DHEA may greatly aid obese women in losing body weight and fat.

Other advantages of 7 Keto DHEA include: 

  • Muscle development.
  • Increased thyroid gland activity.
  • Immune system booster.
  • Improving memory.
  • Reducing the signs of aging.

More research is needed to determine the efficacy of 7 Keto DHEA for these applications.

So far, both supplements have proven to be safe and effective if the right dose is taken. However, more studies are needed to determine the long-term safety of these supplements. It is also recommended that you consult your doctor before using these supplements. If you want to boost your mood, energy, appetite and need to

If you are willing to experiment with your diet to boost your mood, energy, appetite, and exercise routine, there is no reason you can’t achieve success with our 7 Keto supplements.

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